Plasminogen activator inhibitor-1 levels in patients with primary varicose vein

Erguzel N., Yetkin E., Erdem G., Erdil N. , Yetkin G., Heper G., ...Daha Fazla

INTERNATIONAL ANGIOLOGY, cilt.31, ss.176-180, 2012 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 31 Konu: 2
  • Basım Tarihi: 2012
  • Sayfa Sayıları: ss.176-180


Aim. Plasmin is involved in extracellular matrix remodeling by activating some matrix metallo-proteinases and degrading extracellular matrix; therefore component of fibrinolytic system such as tissue plasminogen activator and plasminogen activators inhibitors (PAI-1) might have a role in the pathogenesis of vascular remodeling. In our study we aimed to investigate the levels of PAI-1 levels in patients with primary varicose veins (VV) and in their age and gender matched control group.