Nobel Medicus, cilt.5, sa.2, ss.59-64, 2009 (SCI-Expanded, Scopus)
• Objective: The objective of this study is to analyze the sensitivity, specificity, positive and negative diagnostic value of transvaginal ultrasonography (TVUSG), dilatation and curettage (D&C) and hysteroscopy alone or combined which are used in diagnosis of abnormal uterine bleeding and endometrium carcinoma. • Material and Method: Our study includes 113 women, ages varying between 21 and 71, who were admitted to Taksim Training and Research Hospital, Obstetrics and Gynecology Policlinic, suffering from abnormal uterine bleeding (AUB). TVUSG, hysteroscopy and D&C were applied to patients and obtained materials for pathological examination. Then histological findings are compared with ultrasonography and hysteroscopical findings. • Results: There are 3 endometrial cancer patients (2.65%) in 113 AUB cases. 2 of endometrial cancer patients are diagnosed with TVUSG, 1 case could not diagnosed with TVUSG. But with hysteroscopy and D&C, all 3 cases have been diagnosed. When all methods are taken into consideration, in patients complaining from AUB, polyps are leading cause with 30.08 %. Polyps are followed by myoma uteri with 18.58%, endometrial hyperplasia 16.81%, endometrium carcinoma 2.65%. In a group of patients (7.96%), polyp and myoma are found together. Any organic disease is not established in 23.89% of patients complaining from AUB. • Conclusion: It has been found that the diagnostic value of hysteroscopy is higher than TVUSG. The specifity of D&C for uterine lesions and the positive diagnostic value is higher than TVUSG and hysteroscopy. During the diagnosis of endometrial carcinoma, TVUSG has lower sensitivity and specificity than hysteroscopy and D&C. D&C and hysteroscopy has sensitivity and specificity of 100%.