Clinicopathological Features of Two Extremely Rare Hepatocellular Carcinoma Variants: a Brief Review of Fibrolamellar and Scirrhous Hepatocellular Carcinoma
JOURNAL OF GASTROINTESTINAL CANCER, vol.51, no.4, pp.1187-1192, 2020 (ESCI, Scopus)
- Publication Type: Article / Review
- Volume: 51 Issue: 4
- Publication Date: 2020
- Doi Number: 10.1007/s12029-020-00500-1
- Journal Name: JOURNAL OF GASTROINTESTINAL CANCER
- Journal Indexes: Emerging Sources Citation Index (ESCI), Scopus, EMBASE, MEDLINE
- Page Numbers: pp.1187-1192
- Keywords: Fibrolamellar hepatocellular carcinoma, Scirrhous hepatocellular carcinoma, Tumors, LIVER, DNAJB1-PRKACA, EXPRESSION, HISTOPATHOLOGY, CLASSIFICATION, SURVIVAL, TUMOR, CT
- Inonu University Affiliated: Yes
Abstract
Purpose We aimed to distinguish between fibrolamellar hepatocellular carcinoma and scirrhous hepatocellular carcinoma histopathologically. Methods and results In this review, fibrolamellar hepatocellular carcinoma and scirrhous hepatocellular carcinoma two specific and rare variants of hepatocellular carcinoma, which are difficult to diagnose histopathologically are discussed. Conclusion The clinical, radiological, gross, histopathological, immunohistochemical, and molecular features of these two tumors, which are defined by the World Health Organization (WHO), are mentioned.