Clinicopathological Features of Two Extremely Rare Hepatocellular Carcinoma Variants: a Brief Review of Fibrolamellar and Scirrhous Hepatocellular Carcinoma

ŞAMDANCI E., AKATLI A. N., KARADAĞ SOYLU N.

JOURNAL OF GASTROINTESTINAL CANCER, cilt.51, sa.4, ss.1187-1192, 2020 (ESCI) identifier identifier identifier

  • Yayın Türü: Makale / Derleme
  • Cilt numarası: 51 Sayı: 4
  • Basım Tarihi: 2020
  • Doi Numarası: 10.1007/s12029-020-00500-1
  • Dergi Adı: JOURNAL OF GASTROINTESTINAL CANCER
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, EMBASE, MEDLINE
  • Sayfa Sayıları: ss.1187-1192
  • Anahtar Kelimeler: Fibrolamellar hepatocellular carcinoma, Scirrhous hepatocellular carcinoma, Tumors, LIVER, DNAJB1-PRKACA, EXPRESSION, HISTOPATHOLOGY, CLASSIFICATION, SURVIVAL, TUMOR, CT
  • İnönü Üniversitesi Adresli: Evet

Özet

Purpose We aimed to distinguish between fibrolamellar hepatocellular carcinoma and scirrhous hepatocellular carcinoma histopathologically. Methods and results In this review, fibrolamellar hepatocellular carcinoma and scirrhous hepatocellular carcinoma two specific and rare variants of hepatocellular carcinoma, which are difficult to diagnose histopathologically are discussed. Conclusion The clinical, radiological, gross, histopathological, immunohistochemical, and molecular features of these two tumors, which are defined by the World Health Organization (WHO), are mentioned.