JOURNAL OF PHARMACY AND PHARMACOLOGY, vol.68, no.6, pp.781-790, 2016 (SCI-Expanded)
Objectives According to Biopharmaceutics Classification System (BCS), acyclovir is a class III (high solubility, low permeability) compound, and it is transported through paracellular route by passive diffusion. The aim of this study was to investigate the effect of various pharmaceutical excipients on the intestinal permeability of acyclovir.