Aminoguanidine mitigates apoptosis, testicular seminiferous tubules damage, and oxidative stress in streptozotocin-induced diabetic rats

ORMAN D., VARDI N., ATEŞ B., TASLIDERE E., Elbe H.

TISSUE & CELL, cilt.47, sa.3, ss.284-290, 2015 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 47 Sayı: 3
  • Basım Tarihi: 2015
  • Doi Numarası: 10.1016/j.tice.2015.03.006
  • Dergi Adı: TISSUE & CELL
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.284-290
  • Anahtar Kelimeler: Aminoguanidine, Diabetes, Nitric oxide, Rat, Testis, NITRIC-OXIDE, LIPID-PEROXIDATION, MELATONIN, MELLITUS, TESTIS, COMPLICATIONS, INFERTILITY, GLYCATION, INJURY
  • İnönü Üniversitesi Adresli: Evet

Özet

This study aimed to investigate the effect of aminoguanidine (AG) against testicular damage streptozotocin (STZ) induced diabetes. Thirty two rats were separated into four groups: control, AG, STZ and STZ + AG.