Evaluation of Transcranial Magnetic Stimulation Efficiency in Major Depressive Disorder Patients: A Magnetic Resonance Spectroscopy Study

ERBAY M. F., Zayman E. P., GÖNENİR ERBAY L., ÜNAL S.

PSYCHIATRY INVESTIGATION, cilt.16, sa.10, ss.745-750, 2019 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 16 Sayı: 10
  • Basım Tarihi: 2019
  • Doi Numarası: 10.30773/pi.2019.07.17.3
  • Dergi Adı: PSYCHIATRY INVESTIGATION
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Social Sciences Citation Index (SSCI), Scopus
  • Sayfa Sayıları: ss.745-750
  • Anahtar Kelimeler: Transcranial magnetic stimulation, Depression, Magnetic resonance spectroscopy, Brain metabolites, FRONTAL WHITE-MATTER, DORSOLATERAL PREFRONTAL CORTEX, ANTERIOR CINGULATE CORTEX, N-ACETYL-ASPARTATE, HUMAN BRAIN, BIOCHEMICAL-ABNORMALITIES, METABOLIC-CHANGES, RTMS, INCREASES, GLUTAMATE
  • İnönü Üniversitesi Adresli: Evet

Özet

Objective Repetitive transcranial magnetic stimulation (rTMS) is an effective treatment for major depressive disorder (MDD). This study evaluated the antidepressant effect of rTMS and examined how it affected N-asetyl aspartate (NAA), choline (Cho), creatine (Cr), lactate (Lac), inyoinositol (mins), glutamate (Glu), glutathione (GSH), and glutamine (Gln) metabolite levels in the left dorsolateral prefrontal cortex (DLPFC) of MDD patients who were not receiving antidepressant medication.