Histopathological evaluation of melatonin as a protective agent in heart injury induced by radiation in a rat model

Gurses I., ÖZEREN M., Serin M., YÜCEL N., ERKAL H. Ş.

PATHOLOGY RESEARCH AND PRACTICE, cilt.210, sa.12, ss.863-871, 2014 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 210 Sayı: 12
  • Basım Tarihi: 2014
  • Doi Numarası: 10.1016/j.prp.2014.08.006
  • Dergi Adı: PATHOLOGY RESEARCH AND PRACTICE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.863-871
  • İnönü Üniversitesi Adresli: Evet

Özet

Introduction: Melatonin is a hormone which is known to be a powerful cardioprotective agent due to its free radical-scavenging properties. This study was carried out to evaluate whether melatonin administration prior to irradiation would have a protective effect on cardiac histopathological changes in an experimental rat model.