RELATIONSHIPS BETWEEN PARKINSON'S DISEASE DEMENTIA AND 25-HYDROXY VITAMIN D AND BRAIN-DERIVED NEUROTROPHIC FACTOR LEVELS

Ekmekyapar T., TÜRKÖZ Y., Erdemli Z., Demirtas Y., ALTINAYAR S.

TURKISH JOURNAL OF GERIATRICS-TURK GERIATRI DERGISI, cilt.24, sa.3, ss.407-415, 2021 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 24 Sayı: 3
  • Basım Tarihi: 2021
  • Doi Numarası: 10.31086/tjgeri.2021.238
  • Dergi Adı: TURKISH JOURNAL OF GERIATRICS-TURK GERIATRI DERGISI
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Social Sciences Citation Index (SSCI), Scopus, Academic Search Premier, EMBASE, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.407-415
  • Anahtar Kelimeler: Parkinson Disease, Dementia, Vitamin D, Brain-Derived Neurotrophic Factor, BDNF MESSENGER-RNA, D SUPPLEMENTATION, SERUM, PREVALENCE, RISK
  • İnönü Üniversitesi Adresli: Evet

Özet

Introduction: Parkinson's disease dementia is an important condition that worsens the quality of life in approximately 30% of parkinson disease patients. Vitamin D deficiency and brain-derived neurotrophic factor have been implicated in the pathogenesis of alzheimer type dementia, parkinson's disease, and many neurodegenerative diseases. The aim of this study was to investigate the relationship between cognitive impairment and 25-hydroxy vitamin D and brain-derived neurotrophic factor levels in parkinson's disease dementia patients.