Effects of antioxidant agents against cyclosporine-induced hepatotoxicity

Akbulut, AHMET; Elbe, Hulya; Eris, Cengiz; Dogan, Zümrüt; Toprak, Gulten; Yalcin, Erhan; Otan, EMRAH; Turkoz, YUSUF

doi:10.1016/j.jss.2014.08.042

Effects of antioxidant agents against cyclosporine-induced hepatotoxicity

Akbulut S., Elbe H., Eris C., Dogan Z., Toprak G., Yalcin E., ...Daha Fazla

JOURNAL OF SURGICAL RESEARCH, cilt.193, ss.658-666, 2015 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 193
Basım Tarihi: 2015
Doi Numarası: 10.1016/j.jss.2014.08.042
Dergi Adı: JOURNAL OF SURGICAL RESEARCH
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.658-666
Anahtar Kelimeler: Cyclosporine, Hepatotoxicity, Antioxidant agents, Ursodeoxycholic acid, Melatonin, Allopurinol, A-INDUCED CARDIOTOXICITY, OXIDATIVE STRESS, URSODEOXYCHOLIC ACID, RAT LIVER, ALLOPURINOL, APOPTOSIS, ERDOSTEINE, MELATONIN, TISSUES, INJURY
İnönü Üniversitesi Adresli: Evet

Özet

Background: To investigate the potential protective antioxidant role of ursodeoxycholic acid (UDCA), melatonin, and allopurinol treatment in cyclosporine (CsA)-induced hepatotoxicity.