MOLECULAR AND CELLULAR BIOCHEMISTRY, cilt.286, ss.125-131, 2006 (SCI İndekslerine Giren Dergi)
Both experimental and clinical studies suggests that oxidative stress plays an important role in the pathogenesis of diabetes mellitus type I and type 2. Hyperglycaemia leads to free radical generation and causes neural degeneration. In the present study we investigated the possible neuroprotective effect of mexiletine against streptozotocin-induced hyperglycaemia in the rat brain and spinal cord.