Comparison of serum NO, TNF-alpha, IL-1 beta, sIL-2R, IL-6 and IL-8 levels with grades of retinopathy in patients with diabetes mellitus

Doganay S., EVEREKLİOĞLU C., Er H., Turkoz Y., Sevinc A., Mehmet N., ...Daha Fazla

EYE, cilt.16, sa.2, ss.163-170, 2002 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 16 Sayı: 2
  • Basım Tarihi: 2002
  • Doi Numarası: 10.1038/sj/eye/6700095
  • Dergi Adı: EYE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.163-170
  • Anahtar Kelimeler: chemokine, cytokine, diabetes mellitus, Griess reaction, immunoassay, interleukin, nitric oxide, TUMOR-NECROSIS-FACTOR, NITRIC-OXIDE, IN-VITRO, IMMUNOASSAY SYSTEM, VITREOUS-HUMOR, INTERLEUKIN-6, DISEASE, CYTOKINES, GROWTH, CELLS
  • İnönü Üniversitesi Adresli: Evet

Özet

Background Vitreal interleukin (IL)-1beta (IL-1beta), IL-6, IL-8, tumor necrosis factor-alpha (TNF-alpha) and nitric oxide (NO) levels have previously been determined in patients with proliferative diabetic retinopathy (PDR). However, at present there is no cohort study linking serum levels of NO and many inflammatory cytokines such as TNF-alpha, IL-1beta, soluble IL-2 receptor (sIL-2R), IL-6 and IL-8 to the grade of the microvascular complications.