Pd-N-Heterocyclic carbene catalysed Suzuki-Miyaura coupling reactions in aqueous medium

KARACA E. Ö., Akkoc M., YAŞAR S., ÖZDEMİR İ.

ARKIVOC, pp.230-239, 2018 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume:
  • Publication Date: 2018
  • Doi Number: 10.24820/ark.5550190.p010.519
  • Journal Name: ARKIVOC
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.230-239
  • Keywords: Suzuki-Miyaura cross-coupling reaction, N-heterocyclic carbene, Pd-PEPPSI complex, C-C bond formation, PALLADIUM COMPLEXES, ARYL CHLORIDES, EFFICIENT CATALYSTS, ROOM-TEMPERATURE, PRE-CATALYSTS, NHC, LIGANDS, PRECATALYSTS, ARYLATION, ACIDS
  • Inonu University Affiliated: Yes

Abstract

A new series of methyl substituted imidazole-based N-heterocyclic carbene (NHC) palladium complexes (PdCl2(L-1)NHC(L-1 =pyridine) is reported. Structural definitions of Pd-PEPPSI complexes were determined by NMR spectroscopy, elemental analysis and LC-MS spectroscopy techniques. To evolve a more efficient catalytic system for electronically different aryl chloride substrates on the Suzuki cross-coupling reaction, complexes were used as pre-catalyst. Activity of palladium(II)-NHC complexes screened under mild reaction conditions in aqueous media. With this catalytic system, the reaction proceeded in moderate or good yields with low catalyst loading (0.1 mol%).