Pd-N-Heterocyclic carbene catalysed Suzuki-Miyaura coupling reactions in aqueous medium

KARACA E. Ö., Akkoc M., YAŞAR S., ÖZDEMİR İ.

ARKIVOC, ss.230-239, 2018 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası:
  • Basım Tarihi: 2018
  • Doi Numarası: 10.24820/ark.5550190.p010.519
  • Dergi Adı: ARKIVOC
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.230-239
  • Anahtar Kelimeler: Suzuki-Miyaura cross-coupling reaction, N-heterocyclic carbene, Pd-PEPPSI complex, C-C bond formation, PALLADIUM COMPLEXES, ARYL CHLORIDES, EFFICIENT CATALYSTS, ROOM-TEMPERATURE, PRE-CATALYSTS, NHC, LIGANDS, PRECATALYSTS, ARYLATION, ACIDS
  • İnönü Üniversitesi Adresli: Evet

Özet

A new series of methyl substituted imidazole-based N-heterocyclic carbene (NHC) palladium complexes (PdCl2(L-1)NHC(L-1 =pyridine) is reported. Structural definitions of Pd-PEPPSI complexes were determined by NMR spectroscopy, elemental analysis and LC-MS spectroscopy techniques. To evolve a more efficient catalytic system for electronically different aryl chloride substrates on the Suzuki cross-coupling reaction, complexes were used as pre-catalyst. Activity of palladium(II)-NHC complexes screened under mild reaction conditions in aqueous media. With this catalytic system, the reaction proceeded in moderate or good yields with low catalyst loading (0.1 mol%).