PurposeTo determine the correlation between musculoskeletal system disorders and the physical activity levels of adolescents.MethodsA total of 417 high school students were included in this cross-sectional study. To explain the musculoskeletal pain and physical activity, a self-administered questionnaire which included the Nordic International Physical Activity Questionnaire Short Form (IPAQ-SF) was distributed.ResultsThe standardised Nordic musculoskeletal questionnaire showed that 57.3% of the students reported having musculoskeletal disorders in one or more body parts, and 52.2% of them consisted of girls. The mean weekly energy consumption as linked to the physical activity of the participants was found to be 2534.58 (2371.31) metabolic equivalent task (MET/wk): 45.8% of the individuals exhibited low levels of activity. A statistically significant relationship was found between experiencing upper/low back pain and the participants' low physical activity levels.Conclusions p id=Par4The current study has shown that the prevalence of MSDs was high among high school students, with a correlation being found between low physical activity and back pain. Physical activity levels should hence be considered when evaluating adolescents with musculoskeletal disorders.