Vermicompost helps soil to retain water, regulate soil temperature and structure, and helps solve the soil's nutrient problem. The aim of our study was to compare chemical fertilization with different rates of vermicompost treatments in terms of growth properties, yield, and nutrient element content of spinach (Spinacia oleracea L.). We also determined the appropriate rate of vermicompost application for spinach The experiment was repeated in two successive seasons with five treatments in the experiment: (1) control, (2) 1 ton vermicompost/ha, (3) 2 tons vermicompost/ha, (4) 3 tons vermicompost/ha, and (5) chemical fertilization. To assess the effect of the treatments in spinach, soil analysis (soil texture, pH, EC (Electrical Conductivity), percent of calcium carbonate, organic matter, and macro and micro elements), plant height and yield of spinach plants, and plant nutrient element analysis of spinach leaves were performed. Evaluation of the results indicated that vermicompost had positive impacts on the soil and the plant; the best treatment rate was 3 t/ha. This vermicompost application rate resulted in a 149% yield increase compared with the chemical fertilizer treatment.