Three novel mutations in the apolipoprotein E gene in a sample of individuals with type 2 diabetes mellitus

STEPHENS, JW; Sozen, MUSTAFA; WHITTALL, RA; CASLAKE, MJ; BEDFORD, D; ACHARYA, J; HUREL, SJ; HUMPHRIES, SE

doi:10.1373/j.clinchem.2004.040121

Three novel mutations in the apolipoprotein E gene in a sample of individuals with type 2 diabetes mellitus

STEPHENS J., Sozen M. M., WHITTALL R., CASLAKE M., BEDFORD D., ACHARYA J., ...Daha Fazla

CLINICAL CHEMISTRY, cilt.51, sa.1, ss.119-124, 2005 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 51 Sayı: 1
Basım Tarihi: 2005
Doi Numarası: 10.1373/j.clinchem.2004.040121
Dergi Adı: CLINICAL CHEMISTRY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.119-124
İnönü Üniversitesi Adresli: Hayır

Özet

Background: Apolipoprotein E (apoE) is found in association with triglyceride-rich lipoproteins and is the ligand for the removal of these particles from the plasma. Genetic variations in exon 4 lead to three common gene variants: E2, E3, and E4.