N-Heterocyclic carbene-palladium catalysts for the direct arylation of pyrrole derivatives with aryl chlorides
BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY, cilt.9, ss.303-312, 2013 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 9
- Basım Tarihi: 2013
- Doi Numarası: 10.3762/bjoc.9.35
- Dergi Adı: BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.303-312
- Anahtar Kelimeler: aryl chlorides, atom-economy, C-H bond activation, C-H functionalization, carbenes, palladium, pyrroles, ORGANOMETALLIC CATALYSIS, HETEROAROMATIC-COMPOUNDS, METAL-COMPLEXES, BOND FORMATION, NHC LIGANDS, PHOSPHINES, BROMIDES, AMINATION, C-2
- İnönü Üniversitesi Adresli: Evet
Özet
New Pd-NHC complexes have been synthesized and employed for palladium-catalyzed direct arylation of pyrrole derivatives by using electron-deficient aryl chlorides as coupling partners. The desired coupling products were obtained in moderate to good yields by using 1 mol % of these air-stable palladium complexes. This is an advantage compared to the procedures employing air-sensitive phosphines, which have been previously shown to promote the coupling of aryl chlorides with heteroarenes.