N-Heterocyclic carbene-palladium catalysts for the direct arylation of pyrrole derivatives with aryl chlorides

ÖZDEMİR İ., GÜRBÜZ N., KALOGLU N., DOGAN O., KALOĞLU M., BRUNEAU C., ...Daha Fazla

BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY, cilt.9, ss.303-312, 2013 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 9
  • Basım Tarihi: 2013
  • Doi Numarası: 10.3762/bjoc.9.35
  • Dergi Adı: BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.303-312
  • Anahtar Kelimeler: aryl chlorides, atom-economy, C-H bond activation, C-H functionalization, carbenes, palladium, pyrroles, ORGANOMETALLIC CATALYSIS, HETEROAROMATIC-COMPOUNDS, METAL-COMPLEXES, BOND FORMATION, NHC LIGANDS, PHOSPHINES, BROMIDES, AMINATION, C-2
  • İnönü Üniversitesi Adresli: Evet

Özet

New Pd-NHC complexes have been synthesized and employed for palladium-catalyzed direct arylation of pyrrole derivatives by using electron-deficient aryl chlorides as coupling partners. The desired coupling products were obtained in moderate to good yields by using 1 mol % of these air-stable palladium complexes. This is an advantage compared to the procedures employing air-sensitive phosphines, which have been previously shown to promote the coupling of aryl chlorides with heteroarenes.