Polyenylphosphatidylcholine pretreatment ameliorates ischemic acute renal injury in rats.


Demirbilek S., Karaman A., Baykarabulut A., Akin M., Gurunluoglu K., Turkmen E., ...More

International journal of urology : official journal of the Japanese Urological Association, vol.13, no.6, pp.747-53, 2006 (SCI-Expanded, Scopus)

  • Publication Type: Article / Article
  • Volume: 13 Issue: 6
  • Publication Date: 2006
  • Doi Number: 10.1111/j.1442-2042.2006.01397.x
  • Journal Name: International journal of urology : official journal of the Japanese Urological Association
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.747-53
  • Keywords: ischemia reperfusion, kidney, neutrophil infiltration, nuclear factor kappa beta, oxidative stress, polyenylphosphatidylcholine, NF-KAPPA-B, REPERFUSION INJURY, ISCHEMIA/REPERFUSION INJURY, OXIDATIVE STRESS, POLYUNSATURATED PHOSPHATIDYLCHOLINE, FREE-RADICALS, ANTIOXIDANT, FAILURE, DAMAGE, ALPHA
  • Inonu University Affiliated: Yes

Abstract

Aim: Polyenylphosphatidycholine has been demonstrated to have antioxidant, cytoprotective and anti-inflammatory effects. Whether polyenylphosphatidycholine pretreatment affects ischemia/reperfusion-induced renal damage in vivo is not known and was investigated here in rats.