Synthesis of Quinoxaline-Linked Bis(Benzimidazolium) Salts and Their Catalytic Application in Palladium-Catalyzed Direct Arylation of Heteroarenes
CATALYSIS LETTERS, vol.152, no.7, pp.2012-2024, 2022 (SCI-Expanded, Scopus)
- Publication Type: Article / Article
- Volume: 152 Issue: 7
- Publication Date: 2022
- Doi Number: 10.1007/s10562-021-03787-2
- Journal Name: CATALYSIS LETTERS
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, PASCAL, Chemical Abstracts Core, Chimica, Compendex
- Page Numbers: pp.2012-2024
- Keywords: N-Heterocyclic carbene, Quinoxaline, Multidentate ligand, Palladium, Catalysis, Direct arylation, Heteroarene, HETEROCYCLIC CARBENE COMPLEXES, CROSS-COUPLING REACTIONS, H BOND ARYLATION, ARYL BROMIDES, STRUCTURAL-CHARACTERIZATION, PRECURSORS SYNTHESIS, PINCER COMPLEXES, NICKEL-COMPLEXES, NHC COMPLEXES, LIGANDS
- Inonu University Affiliated: Yes
Abstract
In this study, quinoxaline-linked bis(benzimidazolium) salts were synthesized as bis-N-heterocyclic carbene (NHC) precursors. These bis(NHC) precursors were used as multidentate ligands for the construction of bi(hetero)aryls by palladium-catalyzed direct C-H activation process. The in situ prepared palladium complexes by mixtures of the Pd(OAc)(2) and the bis(NHC) precursors were used as the catalyst for direct C-H activation of heteroarenes. These catalytic system exhibited a modest catalytic activity in the direct C-H activation of five-membered heteroarenes with a wide range of (hetero)aryl bromides.