Analysis of urine biomarkers for early determination of acute kidney injury in non-septic and non-asphyxiated critically ill preterm neonates


ELMAS A. T., KARADAĞ A., TABEL Y., ÖZDEMİR R., Otlu G.

JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE, cilt.30, sa.3, ss.302-308, 2017 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 30 Sayı: 3
  • Basım Tarihi: 2017
  • Doi Numarası: 10.3109/14767058.2016.1171311
  • Dergi Adı: JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.302-308
  • Anahtar Kelimeler: Acute kidney injury, kidney injury molecule-1, neutrophil gelatinase associate lipocaline, preterm infants, sistatin-C, urine, GELATINASE-ASSOCIATED LIPOCALIN, BIRTH-WEIGHT INFANTS, ACUTE-RENAL-FAILURE, INTENSIVE-CARE-UNIT, SERUM CYSTATIN-C, PROMISING BIOMARKER, PREMATURE-INFANTS, CARDIAC-SURGERY, MOLECULE-1, SEPSIS
  • İnönü Üniversitesi Adresli: Evet

Özet

Objective: We designed the present study to test the hypothesis that urinary biomarkers might predict acute kidney injury (AKI) development in non-septic and non-asphyxiated critically ill preterm infants. We evaluated urine (u) sistatin-C (uCys-C), kidney injury molecule-1 (uKIM-1) and neutrophil gelatinase associate lipocaline (uNGAL) as markers of AKI.