Does Chrysin prevent severe lung damage in Hyperoxia-Induced lung injury Model?

Özdemir R., Gökce İ. K., Taşlıdere A., Tanbek K., Gul C. C., Sandal S., ...Daha Fazla

INTERNATIONAL IMMUNOPHARMACOLOGY, cilt.99, 2021 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 99
  • Basım Tarihi: 2021
  • Doi Numarası: 10.1016/j.intimp.2021.108033
  • Dergi Adı: INTERNATIONAL IMMUNOPHARMACOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, BIOSIS, Biotechnology Research Abstracts, CAB Abstracts, Chemical Abstracts Core, EMBASE, MEDLINE, Veterinary Science Database
  • Anahtar Kelimeler: Bronchopulmonary Dysplasia, Chronic Lung Disease, Chrysin, Newborn, Antioxidant, Antiinflammatory, Hyperoxia-Induced Lung Injury, BRONCHOPULMONARY DYSPLASIA, OXIDATIVE STRESS, INFLAMMATION, PROTECTS, RATS, MICE
  • İnönü Üniversitesi Adresli: Evet

Özet

Background: Oxidative stress and inflammation play a critical role in the etiopathogenesis of bronchopulmonary dysplasia (BPD). The aim of this study was to evaluate the preventive effect of Chrysin (CH), an antioxidant, antiinflammatory, antiapoptotic and antifibrotic drug, on hyperoxia-induced lung injury in a neonatal rat model.