Do histopathologic findings improve by increasing the sample size in cholecystectomies?
WORLD JOURNAL OF SURGICAL ONCOLOGY, vol.11, 2013 (SCI-Expanded, Scopus)
- Publication Type: Article / Article
- Volume: 11
- Publication Date: 2013
- Doi Number: 10.1186/1477-7819-11-245
- Journal Name: WORLD JOURNAL OF SURGICAL ONCOLOGY
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Keywords: Cholecystectomy, Sample size, Precancerous lesion, GALLBLADDER CARCINOMA, PRECURSOR LESIONS, CANCER, POLYPS
- Open Archive Collection: AVESIS Open Access Collection
- Inonu University Affiliated: No
Abstract
Background: Gallbladder diseases present with cholelithiasis in a wide spectrum of adenomas and cancers. Two or three specimens are sampled in cholecystectomies in routine pathology practice. The aim of this study was to investigate the increase in frequency of histologic alterations in cholecystectomies, particularly precancerous lesions, by increasing the sample size to understand the carcinoma pathway.