New derivatives of benzimidazole and their antimicrobial activity

CETINKAYA E., Alici B., Gok Y., DURMAZ R., Gunal S.

JOURNAL OF CHEMOTHERAPY, cilt.11, sa.2, ss.83-89, 1999 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 11 Sayı: 2
  • Basım Tarihi: 1999
  • Doi Numarası: 10.1179/joc.1999.11.2.83
  • Dergi Adı: JOURNAL OF CHEMOTHERAPY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.83-89
  • Anahtar Kelimeler: antimicrobials, benzimidazole, benzothiazole, benzoxazole derivatives, CARBENE COMPLEXES
  • İnönü Üniversitesi Adresli: Evet

Özet

Azolium salts and neutral 2-aryl derivatives of benzimidazole, benzothiazole and benzoxazole were synthesized and compounds were identified by H-1 and C-13 NMR spectroscopy and microanalytical methods. In this work the salts I and the neutral compounds 2 were evaluated for their in vitro antimicrobial activity against standard strains: Enterococcus faecalis (ATCC 29212), Staphylococcus aureus (ATCC 29213), Escherichia coli (ATCC 25922), Pseudomonas aeruginosa (ATCC 27853), Candida albicans and Candida tropicals.