Developmental and lethal effects of glyphosate and a glyphosate-based product on Xenopus laevis embryos and tadpoles

ÖZHAN TURHAN D., GÜNGÖRDÜ A., ÖZMEN M.

BULLETIN OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY, vol.104, no.2, pp.173-179, 2020 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 104 Issue: 2
  • Publication Date: 2020
  • Doi Number: 10.1007/s00128-019-02774-z
  • Journal Name: BULLETIN OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, PASCAL, Agricultural & Environmental Science Database, Aqualine, Aquatic Science & Fisheries Abstracts (ASFA), BIOSIS, CAB Abstracts, Chemical Abstracts Core, Chimica, Compendex, EMBASE, Environment Index, Food Science & Technology Abstracts, Greenfile, INSPEC, MEDLINE, Pollution Abstracts, Public Affairs Index, Veterinary Science Database, Civil Engineering Abstracts
  • Page Numbers: pp.173-179
  • Keywords: Xenopus laevis, Glyphosate, Roundup, Toxicity, LIFE STAGES, HERBICIDE ROUNDUP, RISK-ASSESSMENT, TOXICITY, FORMULATIONS, EXPOSURE, METHIDATHION, PESTICIDES, SHRIMP, FIELD
  • Inonu University Affiliated: Yes

Abstract

Effects of pure glyphosate and a glyphosate-based product were evaluated comparatively using two embryonic development stages of Xenopus laevis as model system. When pure glyphosate was applied in pH adjusted media, lethal or developmental effects were not observed at concentrations up to 500 mg L-1. The 96 h LC50 values for the commercial herbicide, in contrast, were 32.1 and 35.1 mg active ingredient L-1 for embryos and tadpoles, respectively. Since pure glyphosate has no effect on the selected biomarkers, it is thought that developmental toxic effects caused by glyphosate-based products are increased mainly due to formulation additives.