Central irisin administration suppresses thyroid hormone production but increases energy consumption in rats

Tekin S., Erden Y., Ozyalın F., Onalan E. E., Çiğremiş Y., Çolak C., ...More

NEUROSCIENCE LETTERS, vol.674, pp.136-141, 2018 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 674
  • Publication Date: 2018
  • Doi Number: 10.1016/j.neulet.2018.03.046
  • Journal Name: NEUROSCIENCE LETTERS
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.136-141
  • Keywords: Irisin, HPT axis, Thyroid hormones, Energy metabolism, Uncoupling proteins, CIRCULATING IRISIN, FOOD-INTAKE, UNCOUPLING PROTEINS, FEEDING-BEHAVIOR, ADIPOSE-TISSUE, OBESITY, MYOKINE, MUSCLE, EXPRESSION, EXERCISE
  • Inonu University Affiliated: Yes

Abstract

Irisin, which is secreted from the skeletal muscle in response to physical exercise and defined as a thermogenic peptide, may play an important role in energy metabolism. Thyroid hormones, which are one of the other influential factors on the metabolic status, increase heat production and are the main regulators of energy metabolism. This study was conducted to determine the possible effects of irisin administration on thyroid hormones.