Does the preference of peripheral versus central venous access in peripheral blood stem cell collection/yield change stem cell kinetics in autologous stem cell transplantation?

Dogu M. H., KAYA E., Berber İ., SARI İ., Tekgunduz E., ERKURT M. A., ...Daha Fazla

TRANSFUSION AND APHERESIS SCIENCE, cilt.54, sa.1, ss.76-79, 2016 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 54 Sayı: 1
  • Basım Tarihi: 2016
  • Doi Numarası: 10.1016/j.transci.2016.01.017
  • Dergi Adı: TRANSFUSION AND APHERESIS SCIENCE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.76-79
  • Anahtar Kelimeler: Autologous stem cell transplantation, Mobilization, Apheresis, MULTIPLE-MYELOMA, MARROW TRANSPLANTATION, G-CSF, MOBILIZATION, LYMPHOMA, SEPARATORS, THERAPY, TRENDS, AMICUS, IMPACT
  • İnönü Üniversitesi Adresli: Evet

Özet

Central venous access is often used during apheresis procedure in stem cell collection. The aim of the present study was to evaluate whether central or peripheral venous access has an effect on stem cell yield and the kinetics of the procedure and the product in patients undergoing ASCT after high dose therapy. A total of 327 patients were retrospectively reviewed. The use of peripheral venous access for stem cell yield was significantly more frequent in males compared to females (p = 0.005). Total volume of the product was significantly lower in central venous access group (p = 0.046). As being a less invasive procedure, peripheral venous access can be used for stem cell yield in eligible selected patients. (c) 2016 Elsevier Ltd. All rights reserved.