Kaposi's sarcoma after liver transplantation from a donor with a history of ventriculoperitoneal shunt and craniotomy for primary central nervous system lymphoma: Report of a case

IŞIK B., YILMAZ S., Kirimlioglu V., Kirimlioglu H., YILMAZ M., Sogutlu G., ...More

SURGERY TODAY, vol.38, no.1, pp.90-94, 2008 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 38 Issue: 1
  • Publication Date: 2008
  • Doi Number: 10.1007/s00595-007-3565-x
  • Journal Name: SURGERY TODAY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.90-94
  • Keywords: donor, Kaposi's sarcoma, lymphoma, ORGAN DONORS, ALLOGRAFT RECIPIENTS, TUMOR TRANSMISSION, MALIGNANCIES, REGISTRY, DISEASE, CANCER, GLIOBLASTOMA, RISK
  • Inonu University Affiliated: Yes

Abstract

The transplantation of organs from donors who have undergone shunt surgery or craniotomy for a malignant central nervous system (CNS) tumor is controversial. We report a case of Kaposi's sarcoma (KS) developing as a result of immunosuppression in the recipient of a liver transplant from a donor who underwent craniotomy and ventriculoperitoneal shunt surgery for primary CNS lymphoma. Polymerase chain reaction assay did not isolate human herpes virus-8 in the Kaposi lesions. To our knowledge, this is the only case ever reported of KS developing after liver transplantation from a donor with lymphoma. Thus, with appropriate screening to exclude possible dissemination, patients with a history of high-grade primary CNS lymphoma treated by ventriculoperitoneal shunt and craniotomy may be accepted as donors.