Palladium-catalyzed Suzuki-Miyaura reaction of aryl chlorides in aqueous media using tetrahydrodiazepinium salts as carbene ligands

Ozdemir I., Gurbuz N., GOK Y., CETINKAYA E., CETINKAYA B.

SYNLETT, no.15, pp.2394-2396, 2005 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: Issue: 15
  • Publication Date: 2005
  • Doi Number: 10.1055/s-2005-872673
  • Journal Name: SYNLETT
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.2394-2396
  • Inonu University Affiliated: Yes


A highly effective, easy to handle, and environmentally benign process for palladium-mediated Suzuki cross-coupling was developed. The in situ prepared three-component system of Pd(OAc)(2), 1,3-dialkyltetrahydrodiazepinium chlorides (2a-e), and K2CO3 catalyzes quantitatively the Suzuki-Miyaura cross-coupling of deactivated aryl chloride.