Synthesis and antimicrobial activity of Ag(I)-N-heterocyclic carbene complexes derived from benzimidazol-2-ylidene

ÖZDEMİR İ., GÜRBÜZ N., DOGAN O., GÜNAL S., ÖZDEMİR İ.

APPLIED ORGANOMETALLIC CHEMISTRY, cilt.24, sa.11, ss.758-762, 2010 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 24 Sayı: 11
  • Basım Tarihi: 2010
  • Doi Numarası: 10.1002/aoc.1693
  • Dergi Adı: APPLIED ORGANOMETALLIC CHEMISTRY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.758-762
  • Anahtar Kelimeler: silver complex, N-heterocyclic carbene, benzimidazole, antimicrobial activity, N-HETEROCYCLIC CARBENES, STRUCTURAL-CHARACTERIZATION, CATALYTIC-ACTIVITY, METAL-COMPLEXES, SILVER, TRANSMETALATION, CHEMISTRY, PALLADIUM, RHODIUM
  • İnönü Üniversitesi Adresli: Evet

Özet

Novel benzimidazol-2-ylidene carbene complexes of Ag(I) were prepared by interaction of the corresponding benzimidazolium salt with Ag2O in dichloromethane. Their structures were characterized by elemental analyses, H-1-NMR, C-13-NMR and IR spectroscopy techniques. All compounds studied in this work were screened for their in vitro antimicrobial activities against the standard strains: Enterococcus faecalis (ATCC 29212), Staphylococcus aureus (ATCC 29213), Escherichia coli (ATCC 25922), Pseudomonas aeruginosa (ATCC 27853) and the fungi Candida albicans and Candida tropicalis. The new complexes were found to be effective antimicrobial activity against a series of bacteria and fungi. Copyright (C) 2010 John Wiley & Sons, Ltd.