The association between vitamin D receptor polymorphisms and multiple sclerosis in a Turkish population

KAMIŞLI Ö., ACAR C., SÖZEN M. M., TECELLİOĞLU M., Yucel F. E., Vaizoglu D., ...More

MULTIPLE SCLEROSIS AND RELATED DISORDERS, vol.20, pp.78-81, 2018 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 20
  • Publication Date: 2018
  • Doi Number: 10.1016/j.msard.2018.01.002
  • Journal Name: MULTIPLE SCLEROSIS AND RELATED DISORDERS
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.78-81
  • Keywords: Multiple sclerosis, Vitamin D, Vitamin D receptor, Polymorphism, GENE POLYMORPHISMS, RISK, METAANALYSIS, AUTOIMMUNITY, JAPANESE, DISEASE
  • Inonu University Affiliated: Yes

Abstract

Background: Multiple sclerosis (MS) is a chronic, demyelinating disease of the central nervous system (CNS). Genetic and environmental factors are important in disease development. Many studies have investigated the relationship between MS and VDR polymorphisms. VDR gene polymorphism has not been previously studied in Turkish MS patients. We aimed to investigate the relationship between MS and VDR genotypes Taq I, Apa I and Fok I polymorphisms in a Turkish population.