Synthesis and Antimicrobial Activity of Novel Ag-N-Heterocyclic Carbene Complexes
MOLECULES, vol.15, no.4, pp.2499-2508, 2010 (SCI-Expanded, Scopus)
- Publication Type: Article / Article
- Volume: 15 Issue: 4
- Publication Date: 2010
- Doi Number: 10.3390/molecules15042499
- Journal Name: MOLECULES
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Page Numbers: pp.2499-2508
- Keywords: N-Heterocyclic carbene, silver complexes, antimicrobial activity, imidazolidin-2-ylidene, IN-VITRO, STRUCTURAL-CHARACTERIZATION, SILVER COMPLEXES, POLYMERS, ACID, DINUCLEAR, LIGANDS
- Inonu University Affiliated: Yes
Abstract
A series of imidazolidinium ligand precursors are metallated with Ag2O to give silver(I) N-heterocyclic carbene complexes. All compounds were fully characterized by elemental analyses, H-1-NMR, C-13-NMR and IR spectroscopy techniques. All compounds studied in this work were screened for their in vitro antimicrobial activities against the standard strains: Enterococcus faecalis (ATCC 29212), Staphylococcus aureus (ATCC 29213), Escherichia coli (ATCC 25922), Pseudomonas aeruginosa (ATCC 27853) and the fungi Candida albicans and Candida tropicalis. The new imidazolidin-2-ylidene silver complexes have been found to display effective antimicrobial activity against a series of bacteria and fungi.