Synthesis and Antimicrobial Activity of Novel Ag-N-Heterocyclic Carbene Complexes

ÖZDEMİR İ., Ozcan E. Ö., GÜNAL S., GÜRBÜZ N.

MOLECULES, cilt.15, sa.4, ss.2499-2508, 2010 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 15 Sayı: 4
  • Basım Tarihi: 2010
  • Doi Numarası: 10.3390/molecules15042499
  • Dergi Adı: MOLECULES
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.2499-2508
  • Anahtar Kelimeler: N-Heterocyclic carbene, silver complexes, antimicrobial activity, imidazolidin-2-ylidene, IN-VITRO, STRUCTURAL-CHARACTERIZATION, SILVER COMPLEXES, POLYMERS, ACID, DINUCLEAR, LIGANDS
  • İnönü Üniversitesi Adresli: Evet

Özet

A series of imidazolidinium ligand precursors are metallated with Ag2O to give silver(I) N-heterocyclic carbene complexes. All compounds were fully characterized by elemental analyses, H-1-NMR, C-13-NMR and IR spectroscopy techniques. All compounds studied in this work were screened for their in vitro antimicrobial activities against the standard strains: Enterococcus faecalis (ATCC 29212), Staphylococcus aureus (ATCC 29213), Escherichia coli (ATCC 25922), Pseudomonas aeruginosa (ATCC 27853) and the fungi Candida albicans and Candida tropicalis. The new imidazolidin-2-ylidene silver complexes have been found to display effective antimicrobial activity against a series of bacteria and fungi.