Suzuki-Miyaura reaction of unactivated aryl chlorides using benzimidazol-2-ylidene ligands


Ozdemir I., Gok Y., Gurbuz N., CETINKAYA E., CETINKAYA B.

SYNTHETIC COMMUNICATIONS, vol.34, no.22, pp.4135-4144, 2004 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 34 Issue: 22
  • Publication Date: 2004
  • Doi Number: 10.1081/scc-200036594
  • Journal Name: SYNTHETIC COMMUNICATIONS
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.4135-4144
  • Keywords: Suzuki, carbene, palladium, benz imidazol-2-ylidene, aryl chlorides, phenylboronic acid, CROSS-COUPLING REACTIONS, HETEROCYCLIC CARBENE COMPLEXES, HECK-TYPE REACTIONS, ARYLBORONIC ACIDS, EFFICIENT CATALYSTS, PALLADIUM(II), WATER, ENETETRAMINES, METATHESIS, CONVENIENT
  • Inonu University Affiliated: Yes

Abstract

Four functionalized bis(benzimidazolium) salts (2a-d) have been prepared and characterized by conventional spectroscopic methods and elemental analyses. A highly effective, easy to handle, and environmentally bengin process for palladium-mediated Suzuki cross-coupling was developed. The in situ prepared three-component system Pd(OAc)(2)/bis(benzimidazolium) bromides (2a-d) and Cs2CO3 catalyzes quantitatively the Suzuki cross-coupling of deactivated aryl chloride in aqueous media.