The risk factors of portal vein thrombosis in patients with liver cirrhosis

Cagin Y. F., BİLGİÇ Y., Berber İ., YILDIRIM O., ERDOĞAN M. A., Firat F., ...Daha Fazla

EXPERIMENTAL AND THERAPEUTIC MEDICINE, cilt.17, sa.4, ss.3189-3194, 2019 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 17 Sayı: 4
  • Basım Tarihi: 2019
  • Doi Numarası: 10.3892/etm.2019.7300
  • Dergi Adı: EXPERIMENTAL AND THERAPEUTIC MEDICINE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED)
  • Sayfa Sayıları: ss.3189-3194
  • Anahtar Kelimeler: cirrhosis, portal vein thrombosis, risk factors, BUDD-CHIARI-SYNDROME, FACTOR-V-LEIDEN, VENOUS THROMBOEMBOLISM, SPLENECTOMY, PREVALENCE, COAGULOPATHY, HEMOSTASIS, DISORDERS, PROTECT
  • İnönü Üniversitesi Adresli: Evet

Özet

This study was designed to identify and assess risk factors for portal vein thrombosis (PVT) in patients with cirrhosis. A total of 98 cirrhosis patients with PVT were identified and 101 cirrhosis patients without PVT were chosen as the control group in this retrospective study. Several variables were measured and the two groups PVT and non-PVT were compared statistically. PVT was identified in 98 patients (10%). Significant differences in hematocrit, international normalized ratio, albumin, bilirubin and glucose were determined between the groups (P<0.05). Out of the thrombophilic risk factors in the patients with PVT factor V Leiden was identified in 8.8%, prothrombin gene 6.6% and methylenetetrahydrofolate reductase 2.2%. There was no difference in survival time between groups (P>0.05).