Plasminogen activator inhibitor-1 levels in patients with primary varicose vein

Erguzel N., Yetkin E., Erdem G., Erdil N., Yetkin G., Heper G., ...More

INTERNATIONAL ANGIOLOGY, vol.31, no.2, pp.176-180, 2012 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 31 Issue: 2
  • Publication Date: 2012
  • Journal Name: INTERNATIONAL ANGIOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.176-180
  • Inonu University Affiliated: Yes

Abstract

Aim. Plasmin is involved in extracellular matrix remodeling by activating some matrix metallo-proteinases and degrading extracellular matrix; therefore component of fibrinolytic system such as tissue plasminogen activator and plasminogen activators inhibitors (PAI-1) might have a role in the pathogenesis of vascular remodeling. In our study we aimed to investigate the levels of PAI-1 levels in patients with primary varicose veins (VV) and in their age and gender matched control group.