Protective effects of chronic melatonin treatment against renal ischemia/reperfusion injury in streptozotocin-induced diabetic rats

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KURCER Z., Parlakpinar H., VARDI N., TASDEMIR S., IRAZ M., FADILLIOGLU E., ...More

EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES, vol.115, no.6, pp.365-371, 2007 (SCI-Expanded)

• Publication Type: Article / Article
• Volume: 115 Issue: 6
• Publication Date: 2007
• Doi Number: 10.1055/s-2007-971056
• Journal Name: EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES
• Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
• Page Numbers: pp.365-371
• Keywords: cardiovascular risk management, cardiovascular incidences, diabetes, autoimmunity, oxidative stress, metabolic features, ISCHEMIA-REPERFUSION INJURY, NITRIC-OXIDE, LIPID-PEROXIDATION, OXIDATIVE STRESS, FREE-RADICALS, HIGH GLUCOSE, ANTIOXIDANT, NEPHROPATHY, FAILURE, REDUCTION
• Inonu University Affiliated: Yes

Abstract

Aims: The purpose of this study was to investigate the effects of chronic administration of melatonin on renal ischemia/reperfusion (IR) injury in streptozotocin (STZ)-induced diabetic rats.