Cytotoxic effect of endemic Tchihatchewia isatidea Boiss. from Turkey


KIRBAĞ S., KESER S., TEKİN S., Inci S., SANDAL S.

ISRAEL JOURNAL OF PLANT SCIENCES, cilt.68, sa.1-2, ss.161-165, 2021 (SCI-Expanded) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 68 Sayı: 1-2
  • Basım Tarihi: 2021
  • Doi Numarası: 10.1163/22238980-bja10033
  • Dergi Adı: ISRAEL JOURNAL OF PLANT SCIENCES
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, Aquatic Science & Fisheries Abstracts (ASFA), BIOSIS, CAB Abstracts, Jewish Studies Source, Veterinary Science Database
  • Sayfa Sayıları: ss.161-165
  • Anahtar Kelimeler: Tchihatchewia isatidea, paint flower, medical plant, cytotoxic, MTT, BROCCOLI SPROUTS, MEDICINAL-PLANTS, BRASSICACEAE
  • İnönü Üniversitesi Adresli: Evet

Özet

Tchihatchewia isatidea Boiss (Brassicaceae) is known among the public as "Reddish Bride", "Paint and Bridal Flower". Flower parts are used for painting and flowering branches for treatment of cough. In this study, anticancer properties of water, ethanol and methanol extracts of Tchihatch-ewia isatidea flower parts were investigated against human breast (MCF-7), human colon (HCT-116) and human prostate (LNCaP) cancer cell lines. Changes in the viability of cancer cells were de-tected by utilizing 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) method. Studies have shown that there is a statistically significant decrease in the cell viability of human breast cancer (MCF-7), colon (HCT-116) and prostate (LNCaP) cancer cells when extracts of T. isati-dea water, ethanol and methanol are used.