Schiff base-Poloxamer P85 combination demonstrates chemotherapeutic effect on prostate cancer cells in vitro

Demirci S., Dogan A., BAŞAK TÜRKMEN N., TELCİ D., Rizvanov A. A., ŞAHİN F.

BIOMEDICINE & PHARMACOTHERAPY, cilt.86, ss.492-501, 2017 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 86
  • Basım Tarihi: 2017
  • Doi Numarası: 10.1016/j.biopha.2016.11.101
  • Dergi Adı: BIOMEDICINE & PHARMACOTHERAPY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.492-501
  • Anahtar Kelimeler: Schiff base, P85, Poloxamer, Prostate cancer, Chemotherapy, PLURONIC P85, ANGIOGENESIS, STATISTICS, DOCETAXEL, DOXORUBICIN, INHIBITION
  • İnönü Üniversitesi Adresli: Evet

Özet

Prostate cancer is a multistep and complicated cancer type that is regulated by androgens at the cellular level and remains the second commonest cause of death among men. Discovery and development of novel chemotherapeutic agents enabling rapid tumor cell death with minimal toxic effects to healthy tissues might greatly improve the safety of chemotherapy.