Metabolomics analysis of seminal plasma in patients with idiopathic Oligoasthenoteratozoospermia using high-resolution NMR spectroscopy

Mumcu A., Karaer A., Dogan B., Tuncay G.

Andrology, vol.8, no.2, pp.450-456, 2020 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 8 Issue: 2
  • Publication Date: 2020
  • Doi Number: 10.1111/andr.12707
  • Journal Name: Andrology
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, BIOSIS, CAB Abstracts, EMBASE, MEDLINE, Veterinary Science Database
  • Page Numbers: pp.450-456
  • Keywords: oligoasthenoteratozoospermia, NMR spectroscopy, metabolomics, seminal plasma, MAGNETIC-RESONANCE-SPECTROSCOPY, SEMEN PARAMETERS, MALE-INFERTILITY, MOTILITY, CAPACITATION, METABOLITES, BIOMARKERS, MANAGEMENT, FERTILITY, PROFILES
  • Inonu University Affiliated: Yes

Abstract

Background Male infertility is a global health issue caused by a combination of different factors. Specialists generally rely on semen analysis to diagnose male infertility. However, it is known that diagnostic semen analysis fails to identify about 50% of male infertility disorders. Recently, metabolomics has been proven to be a powerful technique for the diagnosis of different diseases.