2-Hydroxyethyl-Substituted (NHC)Pd(II)PPh3 Complexes: Synthesis, Characterization, Crystal Structure and Its Application on Sonogashira Cross-Coupling Reactions in Aqueous Media


AKTAŞ A., CELEPCİ D. B., GÖK Y., AYGÜN M.

CHEMISTRYSELECT, vol.3, no.39, pp.10932-10937, 2018 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 3 Issue: 39
  • Publication Date: 2018
  • Doi Number: 10.1002/slct.201802519
  • Journal Name: CHEMISTRYSELECT
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.10932-10937
  • Keywords: Crystal structure, N-Heterocyclic carbenes, Palladium complex, Sonogashira reactions, Triphenylphosphine, HETEROCYCLIC CARBENE COMPLEXES, PALLADIUM COMPLEXES, CATALYTIC APPLICATIONS, ORGANIC-SYNTHESIS, SUZUKI-MIYAURA, COPPER FREE, LIGANDS, TRIPHENYLPHOSPHINE, PHOSPHINES, CHEMISTRY
  • Inonu University Affiliated: Yes

Abstract

This study contains the synthesis of the novel series of the 2- hydroxyethyl substituted Pd-based N-heterocyclic carbene (NHC) / triphenylphosphine (PPh3) complexes. The (NHC)Pd(II)PPh3 complexes have been prepared from the PPh3 ligand, replaced by 3-chloro pyridine ligand in (NHC)Pd(II)(3-Cl-pyridine) complexes. The novel 2-hydroxyethyl substituted (NHC)Pd(II)PPh3 complexes have been characterized by using (HNMR)-H-1, C-13 {H-1}NMR, P-31 {H-1}NMR, FTIR spectroscopy, and elemental analysis techniques. Molecular and crystal structure of 1f was obtained by using single-crystal X-ray diffraction method. The novel 2-hydroxyethyl substituted (NHC)Pd(II)PPh3 complexes have been examined as catalysts in the Sonogashira cross-coupling reactions aqueous medium and demonstrated excellent activity in this reaction.