Molecular epidemiology of tuberculosis in Turkey

Durmaz R., Gunal S., Yang Z., Ozerol I., Cave M.

CLINICAL MICROBIOLOGY AND INFECTION, cilt.9, sa.8, ss.873-877, 2003 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 9 Sayı: 8
  • Basım Tarihi: 2003
  • Doi Numarası: 10.1046/j.1469-0691.2003.00654.x
  • Dergi Adı: CLINICAL MICROBIOLOGY AND INFECTION
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.873-877
  • Anahtar Kelimeler: tuberculosis, Mycobacterium tuberculosis, IS6110, molecular epidemiology, MYCOBACTERIUM-TUBERCULOSIS, REPETITIVE-ELEMENT, COMPLEX STRAINS, IS6110, POLYMORPHISM, TRANSMISSION, PTBN12
  • İnönü Üniversitesi Adresli: Evet

Özet

Our objective was to determine the extent of fingerprint pattern diversity of Mycobacterium tuberculosis isolates from Turkey. Of the 320 patient isolates, 81 (25.3%) carried less than or equal to5 copies of IS6110. The combination of two typing procedures on isolates from 317 patients identified 157 strains as unique and clustered 160 isolates in 59 clusters. In spite of the fact that the patients originated from a large geographic area and represented only a small fraction (1.5%) of the patients in the country, 50.5% of the isolates were clustered.