4-Acetylphenyl-Substituted imidazolium salts: Synthesis and characterization

5th International Organic Chemistry Congress, Malatya, Türkiye, 14 - 17 Ekim 2021, ss.38

The N-heterocyclic carbene (NHC) ligands have attracted a lot of interest in the field of organic chemistry because of its

synthetic variability and the ability to adjust the steric and electronic properties. These ligands are known as unique ligands

for the synthesis of industrial catalysts. On the other hand, in recent years, numerous studies have been carried out on the

biological applications of NHC ligands and their metal complexes. In the last few decades, studies on antimicrobial and

anticancer properties of NHC-metal complexes have been reported. In addition, recently enzyme inhibition studies of NHC

ligands such as imidazole, benzimidazole, and imidazolidine have been conducted. NHC ligands have been demonstrated to

be highly active in enzyme inhibition studies [1-5].