Circulating adrenomedullin levels in ankylosing spondylitis and Familial Mediterranean Fever

UERETEN K., OEZBEK M., Oeztuerk M. A., DOGRU I., DOGRU A., Yuerekli M., ...Daha Fazla

JOINT BONE SPINE, cilt.75, sa.3, ss.295-298, 2008 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 75 Sayı: 3
  • Basım Tarihi: 2008
  • Doi Numarası: 10.1016/j.jbspin.2007.09.011
  • Dergi Adı: JOINT BONE SPINE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.295-298
  • İnönü Üniversitesi Adresli: Evet

Özet

Introduction: Adrenomedullin (AM) is a 52-amino acid peptide with vasorelaxant properties. Apart from its roles on vascular tonus, AM can also contribute to inflammatory events. Plasma AM levels were elevated in connective tissue diseases and vasculitic disorders. Ankylosing spondylitis (AS) is a chronic inflammatory disease of the spine initiating in the sacroiliac joints. Familial Mediterranean Fever (FMF) is a hereditary disorder characterized by self-limiting acute attacks of fever and the presence of sustained subclinical inflammation in the attack-free periods. In this study, we investigated plasma AM levels in patients with AS and patients with FMF.