Akademik Veri Yönetim Sistemi
5th International Organic Chemistry Congress, Malatya, Türkiye, 14 - 17 Ekim 2021, ss.49
Organic and organometallic chemistry was indisputably transformed by Arduengo et al who isolated the first free Nheterocyclic
carbene (NHC) in 1991 [1]. Since then, a large number of different NHCs have been synthesized, and this
important class of ligands has been known as excellent candidates for palladium-catalyzed cross‐coupling reactions due to
their superior performance over the more commonly used tertiary phosphines [2]. These ligands are electron-rich Lewis bases
that benefit from stabilization associated with both strong σ-donor and weak π‐acceptor character [3,4]. The biological
activities of compounds containing the sulfonamide group are known [5]. We thought that compounds containing sulfonyl
groups could also be bioactive compounds. In this work, we synthesized the new 4-(methylsulfonyl)benzyl-substituted benzimidazolium salts 1a-f. Also, all of the
compounds have been characterized by using 1H NMR, 13C NMR, FTIR spectroscopy, and elemental analysis techniques.
Also, these compounds were examined against the xanthine oxidase enzyme.